Bioactive compound screening on keratinocyte and/or T lymphocyte models; Lysosomal identity survey

University of Gdańsk (Poland)

MGC: many years of research experience in scientific centers in Poland and abroad, in the field of viral, bacterial and human molecular biology and genetics, nanobiotechnology and electric biochips, molecular medicine concerning genetically determined metabolic diseases and genetically based autoimmune diseases, including skin disorders, and in particular psoriasis, in relation to lysosomal world; committed to work on compounds with properties that promote health and maintain the proper functioning of the human body, especially skin and immune system cells, and potentially responsible for the correction of cellular changes associated with various immuno-genetic diseases, specifically with psoriasis; co-author of 3 industrial implementations. MM: highly engaged in the research area related to lysosomal and autoimmune disorders with broad knowledge and experience gained in Poland and abroad institutes; proficient in in vitro models of metabolic and autoimmune diseases; accustomed in numerous molecular biology laboratory techniques, especially concerning lysosomal function; expert in gene expression analysis. MK: mature achievements in the field of human molecular biology and medical genetics, with laboratory experience including work on units with anti-inflammatory potential in the context of skin inflammation; acquainted with innovative medical markers in the diagnosis and treatment of human fertility, and currently gaining experience in research on lysosomal machinery and autophagy mechanisms in keratinocytes and T lymphocytes under chronic inflammation, especially in relation to psoriasis. All experts are authors or co-authors of multiple articles and conference reports.